The drug Motilium contains active ingridient Domperidone 10mg. It is ant-emitic, dopamine antagonist type of drug. Domperidone main purpose is to treat nausea and vomiting as well as fullness, abdominal bloating, fullness, and discomfort.
It blocks certain dopamine receptors in brain chemoreceptor trigger zone (CTZ). Its mechanism effectively blocks vomiting reflex and stops nausea.
Before taking this pill consult with your doctor. Be aware in case of following:
Any allergic reactions.
There were no studies of Domperidone use by pregnant women and children. Animal tests found no birth defects. No specific information exists about possible harm to children. Domperidone passes into the milk of breast-feeding women, but there is no information of possible negative effects. Make sure to consult your doctor before using Domperidone.
Also consult your doctor before taking this medicine if you have bleeding from stomach, bowel problems, liver disease.
Usual dose of domperidone is 10mg 3-4 times per day, 20-30 min before eat or before sleep. It can be increased to 20 mg 3-4 times a day.
Possible side effects
Long term use is not always recommended.
Lactose and not be suitable for people with intolerance to lactose. Side effects can include the following: breast pain, stomach cramps, diarrhoea, abnormal enlargement of breasts in men, abnormal movements of legs, hands, face, neck and tongue, eg tremor,twitching, rigidity (extrapyramidal effects).
Overdose symptoms can incluse disorientation, drowsiness and extrapyramidal reactions. In these situations anti-parkinson or anticholinergic may be helpful.
Domperidone can interact with following drugs:
• MAO inhibitors (phenelzine)
• HIV protease inhibitors (, indinavir)
• "azole" antifungals ( itraconazole, fluconazole, ketoconazole, miconazole)
• erythromycin antibiotics ( clarithromycin)
Always ask your doctor to decide how to combine those drugs together with domperidone.
Why You Shouldn't Ignore Constipation
When it comes to digestive health, the condition you're most likely to suffer from is constipation. In constipation, infrequent bowel movements cause hard stools that are difficult to pass. You're most likely to struggle with irregular bowel movements if you are an older adult or pregnant, but lifestyle factors, such as a low intake of fiber and fluid or limited activity, also slow bowel transit. Constipation isn't just uncomfortable though, as infrequent bowel movements can signal a medical problem. Here are three reasons to visit your doctor if you suffer from chronic constipation.
A symptom of cancer
Cancers in the colon and rectum can present as constipation. However, it is unusual for irregular bowel movements to be the only symptom of colorectal cancer. Constipation as a cancer symptom is usually seen alongside abdominal pain, rectal bleeding, poor appetite, unintentional weight loss and fatigue. Spotting this collection of possible cancer symptoms early and reporting these signs to your doctor allow them to rule out cancer as a cause of constipation. If you do receive a diagnosis of colorectal cancer though, early treatment increases the likelihood of a successful outcome.
A hormone-related problem
An underactive thyroid, where your thyroid gland produces insufficient hormones, produces numerous symptoms, one of which is constipation. Other signs associated with the slowing of your metabolism include tiredness, weight gain, dry skin and hair, and feeling the cold. It is simple to resolve the symptoms of hypothyroidism through medication, so if you have additional symptoms of an underactive thyroid, make an appointment with your medical practitioner.
If you have poor blood sugar control, you may experience damage to the nerves that control your digestive tract, which can present as constipation, diarrhea, nausea and heartburn. Known as autonomic neuropathy, this type of nerve damage is usually seen in more advanced cases of diabetes, arising from late diagnosis of diabetes or poor compliance with blood glucose control. Input from your doctor, diabetes nurse and dietician can help you achieve better glycemic control and preserve nerve function. Signs of poor blood sugar control include increased thirst, urination and tiredness, recurrent thrush, poor wound healing, weight loss and blurred vision, so these symptoms should always be reported to your physician.
A sign of neurological disease
Constipation is sometimes a symptom of Parkinson's disease, where damage to the brain cells that produce the chemical dopamine affects your muscle function. While tremors, slowed movement and muscle stiffness are common signs of Parkinson's disease, the muscles of your digestive system can also be affected, making them operate slower, which causes constipation. Although medications to treat Parkinson's disease ease symptoms, constipation is a possible side effect of certain drugs to manage this neurological condition.
Infrequent bowel movements are also seen in multiple sclerosis. Constipation may occur as a symptom of multiple sclerosis, as the disease disrupts nerve signals to empty your bowels, stops your pelvic floor muscles relaxing and interferes with your natural urge to visit the bathroom after eating. If you experience altered bowel habits alongside tingling, numbness, poor balance, limb weakness or blurred vision, you should seek medical advice, as this combination of symptoms may suggest multiple sclerosis.
Although changes to dietary intake and exercise habits can help to ease constipation, persistent problems with your bowels require a medical assessment to rule out a more serious cause. Therefore, always book an appointment with your doctor to investigate constipation, particularly if it occurs alongside other new symptoms.
I ordered Domperidone 10mg from online pharmacy, that was recommended by my friend. Got the package in 5 days with express delivery. The drugs were of highest quality. Thanks for great service!
I tried Domperidone 10mg and it is great! Sometimes I had a problems with my stomach after eating fat food, discomfort and nausea. Taking Domperidone 10mg makes all negative symptoms disappear immediately. I recommend it to everyone!
I have to use medication to treat Parkinson Disease, and some of negative side effects of it is nausea. Using Domperidone 10mg helps alot. It's really great that i can buy domperidone 10mg from online pharmacy so easy and cheap. Many thanks!
Several times a year I buy Domperidone on this site. Orders always come quickly and on time. Never experienced any problems. I am very satisfied with the quality of the product and service and the very low price.
A lot of times I bought different things online, but rarely when I get so high quality service. This is exactly the case. I recommend everyone the best Domperidone in the market. Fast and free delivery, quality customer support.
I got a prescription for this drug from my doctor. Generic version of Domperidone which i found here is much more cheaper that in my local store. Seller provided me with all required information and made a quick delivery. Im planning to buy it again in future.
Domperidone is not a universal remedy, but it helps my daughter with her vomiting issues. Im very happy to be able to order Domperidone in this online store with a good discount. The payment system is very easy to use.
Hi there. Domperidone is great and effective anti-vomiting medicine. I tried it first time from this site and got the desired effect. Thank you for the great service.